Using Interceptor Plus

How should I give Interceptor® Plus (milbemycin oxime/praziquantel) to my dog?

You can give Interceptor Plus to your dog by hand or by adding it to a small amount of dog food. Administer the chewables in a manner that encourages your dog to chew, rather than to swallow without chewing. If your dog normally swallows treats whole, you may break the chewables into pieces and feed them to your dog. Make sure that your dog consumes the complete dose, and observe your pet for a few minutes after administration to ensure that no part of the dose is lost or rejected. If you suspect that any of the dose has been lost, redosing is recommended.

Consult your veterinarian regarding the need for year-round administration of Interceptor Plus. To help you remember the monthly dosing schedule, stick-on labels are included for your calendar.

Learn more about dosing & administration

Do I have to give Interceptor Plus with food?

Interceptor Plus may be offered to your dog by hand or by adding to a small amount of dog food. It is not necessary to administer the chewable with a full meal.

Can Interceptor Plus be crushed and put in food?

Interceptor Plus should be administered in a manner that encourages your dog to chew, rather than swallow whole. You may break or crush the chewable into pieces and feed them to your dog, making sure your dog consumes the complete dose. If you suspect that any of the dose has been lost, redosing is recommended.

The package reads "chewable." What if my dog swallows the tablet whole?

Interceptor Plus should be administered in a manner that encourages your dog to chew, rather than swallow whole. However, we do not expect a difference in the effectiveness of the product if your dog consumes it whole.

What if I give more than the prescribed amount of Interceptor Plus to my dog?

Contact your veterinarian as soon as possible if you believe your dog has ingested more than the recommended dose of Interceptor Plus. In studies where dogs were dosed at one, three, or five times the maximum dosage, they exhibited signs consistent with avermectin toxicitiy that followed a dose-related pattern in respect to onset, incidence and duration. Clinical signs included ataxia, decreased activity, tremors, vomiting and salivation.

Should I restrict either my dog’s activity or contact with my dog after the tablet is consumed?

You may maintain normal activities and interactions with your dog.

What if I see worms in my dog’s stool during the month after administration of Interceptor Plus?

Interceptor Plus is indicated to treat and control intestinal parasite infections of adult hookworms, roundworms, whipworms and tapeworms.* In occasional cases, it is possible that the action of Interceptor Plus in killing the intestinal worms will lead to the dog expelling them in stool. If you have questions, consult your veterinarian for measures you can take to prevent a reinfection of intestinal parasites.

*Hookworm (A. caninum), roundworm (T. canis, T. leonina), whipworm (T. vulpis) and tapeworm (T. pisiformis, E. multilocularis, E. granulosus)

Can Interceptor Plus be given to cats?

No. Interceptor Plus is not approved for use in cats. Interceptor Plus was developed exclusively for administration to dogs. If you’re looking for Elanco products that are approved for use in cats, learn more on the Elanco brands page