How to give your dog Interceptor Plus

Interceptor® Plus (milbemycin oxime/praziquantel) is a chewable tablet flavored with real chicken that you give to your dog once a month, every month. Its overall acceptability is 96.6%, which makes dosing easy.

You can give Interceptor Plus to your dog by hand or add it to a small amount of dog food. Administer the chewables in a manner that encourages your dog to chew, rather than to swallow without chewing. If your dog normally swallows treats whole, you may break the chewables into pieces and feed them to your dog.

Make sure that your dog consumes the complete dose, and observe your pet for a few minutes after administration to ensure that no part of the dose is lost or rejected. If you suspect that any of the dose has been lost, redosing is recommended.

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One chew,
every month*
*For heartworm disease prevention, give once monthly for at least 6 months after the last exposure to mosquitoes

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Easy to dose:
96.6% overall acceptability

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Safe for dogs 6 weeks and older
and 2 pounds of body weight or greater


Your veterinarian should test your dog for heartworm infection before prescribing Interceptor Plus. Interceptor Plus is approved for dogs and puppies 6 weeks and older and 2 pounds or greater. The chart below shows the proper dosing for the listed weight ranges and the color of the box containing the appropriate tablet dose.

Interceptor Plus Dosing Chart

Dosing for Interceptor Plus


The American Heartworm Society1 and The Companion Animal Parasite Council2 (CAPC) recommend treating dogs year-round with broad-spectrum parasite protection to help ensure their health. However, if you do not give your dog Interceptor Plus year-round, then the treatment schedule should begin within 1 month of the first seasonal exposure to mosquitoes and should continue until at least 6 months after the last seasonal exposure to mosquitoes.