How to give your dog Interceptor® Plus (milbemycin oxime/praziquantel)

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Safe for dogs 6 weeks and older
and 2 lbs of body weight or greater

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Easy to dose:
96.5% overall acceptability

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One chew,
Once a month*
*For heartworm disease prevention, give once monthly for at least 6 months after the last exposure to mosquitoes.

Interceptor Plus dosing information

Interceptor Plus is proven safe in dogs and puppies 6 weeks and older and 2 pounds or greater. The chart below shows the proper dosing for the listed weight ranges and the color of the box containing the appropriate tablet dose.

Interceptor Plus Dosing Chart

Dosing for Interceptor Plus

Administering Interceptor Plus to your dog

Your veterinarian should test your dog for heartworm infection before prescribing Interceptor Plus.

Interceptor Plus is a chewable tablet flavored with real chicken that you can offer to your dog by hand or added to a small amount of dog food. Plus, its overall acceptability is 96.5%, which makes dosing easy.

Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes after administration to ensure that no part of the dose is lost or rejected. If you suspect that the dose has been lost, redosing is recommended.


The Companion Animal Parasite Council (CAPC), an independent group established to create parasite-control guidelines, recommends treating dogs year-round with broad-spectrum parasite protection to help ensure their health. However, if you do not give your dog Interceptor Plus year-round, then the treatment schedule should begin within one month of the first seasonal exposure to mosquitoes and should continue until at least six months after the last seasonal exposure to mosquitoes.